Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6018037 | Experimental Neurology | 2013 | 10 Pages |
Abstract
Our data suggest that 4-AP while having no apparent immunomodulatory or direct neuroprotective effects, significantly ameliorates conduction abnormalities thereby improving gait and coordination. Improvement of mobility in this experimental model supports trial data and clinical experience with 4-AP in the symptomatic treatment of MS.
Related Topics
Life Sciences
Neuroscience
Neurology
Authors
Kerstin Göbel, Jan-Hendrik Wedell, Alexander M. Herrmann, Lydia Wachsmuth, Susann Pankratz, Stefan Bittner, Thomas Budde, Christoph Kleinschnitz, Cornelius Faber, Heinz Wiendl, Sven G. Meuth,