| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6018181 | Experimental Neurology | 2013 | 11 Pages |
Abstract
⺠We applied Fingolimod, an S1P agonist, in two murine experimental stroke models. ⺠Fingolimod reduced short-term brain edema and neurological deficits after ICH. ⺠T-lymphocytes and cerebral ICAM-1, IFN-γ, and IL-17 were reduced by Fingolimod. ⺠Fingolimod reduced long-term behavioral deficits and brain tissue damage.
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Authors
William B. Rolland, Tim Lekic, Paul R. Krafft, Yu Hasegawa, Orhan Altay, Richard Hartman, Robert Ostrowski, Anatol Manaenko, Jiping Tang, John H. Zhang,