| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6018205 | Experimental Neurology | 2013 | 10 Pages |
Abstract
⺠NF-kB subunits c-rel and p50 are specifically reduced in diabetic DRG neurons. ⺠Insulin specifically increases c-rel and p50 in DRG neurons. ⺠Experimental reduction of NF-kB induces markers of diabetic neuropathy. ⺠Enhancement of NF-kB activity reverses markers of diabetic neuropathy. ⺠Deficient NF-kB causes reduction in antioxidant enzyme MnSOD.
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Authors
A. Saleh, J. Schapansky, D.R. Smith, N. Young, G.L. Odero, B. Aulston, P. Fernyhough, G.W. Glazner,