Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6018430 | Experimental Neurology | 2013 | 11 Pages |
Abstract
⺠In FHD LTP-like plasticity is abnormal (reduced after iTBS and increased after PAS25). ⺠FHD reduces early motor learning and motor retention. ⺠Simple writer's cramp patients move faster than dystonic writer's cramp patients. ⺠The degree of early motor learning correlates with dystonia duration and severity. ⺠Experimentally- and behaviorally-induced LTP-like plasticity are altered in FHD.
Keywords
MEPrTMSTMSFHDBFMITBScTBSSTDPADMAPBRMTAMTtDCSactive motor thresholdISIresting motor thresholdlong-term depressionelectromyographyEMGTranscranial direct current stimulationIntermittent theta burst stimulationRepetitive transcranial magnetic stimulationTranscranial magnetic stimulationPaired associative stimulationContinuous theta burst stimulationlong-term potentiationLTPabductor digiti minimi musclefocal hand dystoniadystoniaFDIFirst dorsal interosseus muscleAbductor pollicis brevis muscleInterstimulus intervalprimary motor cortexLTDPASmotor-evoked potentialPlasticitySpike timing-dependent plasticityWriter's cramp
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Authors
Daniele Belvisi, Antonio Suppa, Luca Marsili, Flavio Di Stasio, Ahmad Khandker Parvez, Rocco Agostino, Giovanni Fabbrini, Alfredo Berardelli,