Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6018543 | Experimental Neurology | 2012 | 9 Pages |
Abstract
⺠We describe novel anti-inflammatory mechanisms of G-CSF in experimental stroke. ⺠Experimental stroke induces maturation and cerebral migration of DCs. ⺠G-CSF suppresses stroke-induced DC migration. ⺠G-CSF suppresses the enhanced maturation process of DCs following experimental stroke. ⺠Inhibited DC functions are associated with an attenuation of cerebral inflammation.
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Authors
Barbara Dietel, Iwona Cicha, Bernd Kallmünzer, Miyuki Tauchi, Atilla Yilmaz, Werner G. Daniel, Stefan Schwab, Christoph D. Garlichs, Rainer Kollmar,