Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6018549 | Experimental Neurology | 2012 | 11 Pages |
Abstract
⺠We investigated side-related changes in response to balance perturbation in early PD. ⺠Toe-down rotation of a platform evokes a medium-latency response (MLR) in the tibialis. ⺠The spinal (MLR1) and supraspinal (MLR2) components are abnormal in the affected side. ⺠Poor MLR1 reduction by holding indicates unilateral impairment of descending control. ⺠Increased MLR2 is related to abnormal basal-ganglia ascending influence to the cortex.
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Authors
Antonio Nardone, Carlo Pasetti, Marco Schieppati,