Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6018569 | Experimental Neurology | 2012 | 8 Pages |
Abstract
⺠Redox-active Cu(II)-Aβ1-40 is more toxic than other biochemical forms of Aβ. ⺠Cu(II)-Aβ causes formation of hyperphosphorylated tau-containing axonal swellings. ⺠Cu(II)-Aβ causes production of free radicals and leakage of K+ from neurons.
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Authors
Claire Howells, Katrina Saar, Emma Eaton, Shannon Ray, Peep Palumaa, Lana Shabala, Paul A. Adlard, William Bennett, Adrian K. West, Gilles J. Guillemin, Roger S. Chung,