Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6018582 | Experimental Neurology | 2012 | 15 Pages |
Abstract
⺠A spinal reflex, wind-up, collapses after peripheral nerve injury. ⺠Lentiviral delivery of ChABC leads to widespread CSPG digestion. ⺠ChABC treatment protects wind-up from PNI-mediated collapse. ⺠Low threshold polysynaptic reflex amplitude increases with ChABC treatment. ⺠Maladaptive plasticity was not detected by behavioral pain testing.
Keywords
Related Topics
Life Sciences
Neuroscience
Neurology
Authors
Karen D. Bosch, Elizabeth J. Bradbury, Joost Verhaagen, James W. Fawcett, Stephen B. McMahon,