| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6018599 | Experimental Neurology | 2012 | 9 Pages |
Abstract
⺠Synaptosomes from HIV/gp12 Tg mice tandem mass tag labeled for MS/MS analysis. ⺠Akt pathway identified as suppressed in HIV/gp12 Tg brains. ⺠Akt pathway also suppressed in human HIV associated neurocognitive disorders (HAND). ⺠Akt is S-nitrosylated in HIV/gp120 and HAND brain. ⺠MS/MS and pathway analysis is means to identify potential drug targets in disease.
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Authors
Sugato Banerjee, Lujian Liao, Rossella Russo, Tomohiro Nakamura, Scott R. McKercher, Shu-ichi Okamoto, Florian Haun, Rana Nikzad, Rameez Zaidi, Emily Holland, Alexey Eroshkin, John R. III, Stuart A. Lipton,