Article ID Journal Published Year Pages File Type
6018680 Experimental Neurology 2012 11 Pages PDF
Abstract
► NRP-derived axons cross borders between laminin and CSPGs. ► NRP growth cones exhibit lower levels of PTPσ and LAR compared to sensory neurons. ► NRP-derived axons cross onto CSPG independent of GRP contact and secreted factors. ► GRPs secrete factors that promote axon outgrowth of sensory neurons onto CSPG. ► GRP secreted factors decrease the inhibitory properties of the CSPG substrata.
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