Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6018688 | Experimental Neurology | 2011 | 5 Pages |
Abstract
⺠Proteasome activity is decreased in the cerebellum of Ts65Dn mice. ⺠The decrease in proteasome activity induces an increase of ubiquitinated proteins. ⺠Ubiquinated proteins are stored into the nucleus of cerebellar large neurons. ⺠Neuronal nuclei are intensely stained by FUS immunocytochemistry.
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Authors
Daniela Necchi, Selene Lomoio, Elda Scherini,