Article ID Journal Published Year Pages File Type
6018694 Experimental Neurology 2011 8 Pages PDF
Abstract
►Chemotherapy-induced peripheral neuropathy (CIPN) is modeled in the rat. ►CIPN-evoked axonal mitochondrial swelling and vacuolation suggest a bioenergetic deficit. ►Mitochondrial respiration and ATP production is impaired in rats with CIPN. ►Chemotherapy-evoked mitotoxicity is a likely cause of CIPN.
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Life Sciences Neuroscience Neurology
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