Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6018715 | Experimental Neurology | 2011 | 9 Pages |
Abstract
⺠New translational approach for IGF-I therapy in motoneuron diseases. ⺠Improved drug properties for IGF-I without loss of biological activity relevant for neuromuscular disorders. ⺠Systemic IGF-I exerts central neuroprotective effects on motoneurons. ⺠Neuroprotection correlates with functional benefits in pmn mice.
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Authors
Sibylle Jablonka, Bettina Holtmann, Michael Sendtner, Friedrich Metzger,