| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6018844 | Experimental Neurology | 2012 | 12 Pages |
Abstract
⺠Blood brain barrier disruption after traumic brain injury is greater in aged than adult mice. ⺠Activation of MMP-9 after traumatic brain injury is greater in aged than adult mice. ⺠Expression of the blood brain barrier structural protein claudin-5 is impaired after traumatic brain injury in aged mice. ⺠Increased blood brain barrier disruption and decreased repair may contribute to poor outcomes after injury to the aged brain.
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Authors
Phil Lee, Jieun Kim, Rachel Williams, Rajat Sandhir, Eugene Gregory, William M. Brooks, Nancy E.J. Berman,