Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6018845 | Experimental Neurology | 2012 | 8 Pages |
Abstract
âºGlyoxalase I protects against damaging effects of advanced glycation end products. âºWe examine two strains of mice that naturally express different levels of GLO1. âºDiabetic BALB/cJ mice with low levels develop several classic signs of neuropathy. âºDiabetic BALB/cByJ mice with high levels do not develop signs of neuropathy. âºThese mice provide a new tool to explore the role of GLO1 and AGE-related damage.
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Authors
M.M. Jack, J.M. Ryals, D.E. Wright,