| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6018867 | Experimental Neurology | 2012 | 12 Pages |
Abstract
⺠Cx43 is the predominantly expressed gap junction protein in MSC and U87 cells. ⺠mRNA expression of Cx43 changes significantly in co-cultured glioma and MSC cells. ⺠Co-culture of glioma cells and MSC shows structural and functional syncytia formation. ⺠Co-culturing in mixed spheroids enhances migration of glioma cells and MSC. ⺠Inhibition of gap junctions reduces cell migration out of spheroids.
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Authors
Christian Schichor, Valerie Albrecht, Benjamin Korte, Alexander Buchner, Rainer Riesenberg, Josef Mysliwietz, Igor Paron, Helena Motaln, Tamara Lah TurnÅ¡ek, Kathrin Jürchott, Joachim Selbig, Joerg-Christian Tonn,