| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6018876 | Experimental Neurology | 2012 | 14 Pages |
Abstract
⺠The chemotherapeutic cisplatin induces cytotoxic effects on CNS. ⺠We examine the changes in the developing CNS during rat postnatal life. ⺠A single injection of cisplatin impaired the hippocampus formation and maturation. ⺠The neurotransmitter patterns and morphology are damaged. ⺠Our model system suggests attention when cisplatin is given during childhood.
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Authors
V.M. Piccolini, S. Cerri, E. Romanelli, G. Bernocchi,