| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6018897 | Experimental Neurology | 2012 | 10 Pages |
Abstract
⺠Suprasacral spinal cord injury (SCI) disrupts urine storage and voiding functions. ⺠SCI alters the morphology, chemistry and electrical properties of bladder afferent neurons ⺠Synaptic remodeling in the spinal micturition reflex pathway occurs after SCI. ⺠Nerve growth factor contributes to neuroplasticity of bladder and sphincter reflexes after SCI.
Keywords
DSDpreganglionic neuronPGNSNMIPSPIDOPMCEPSPSacral neuromodulationgamma-aminobutyric acidSynaptic remodelingNDOIdiopathic detrusor overactivityNeurogenic detrusor overactivityMicturitionafferent nervesnerve growth factorUrinary bladderPontine micturition centerNeuropeptidesexcitatory post synaptic potentialinhibitory postsynaptic potentialGABAUrothelium
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Authors
William C. de Groat, Naoki Yoshimura,