Article ID Journal Published Year Pages File Type
6018960 Experimental Neurology 2012 8 Pages PDF
Abstract
► Exogenous NPCs promote remyelination in a viral model of demyelination. ► The role of Olig1 in NPC-mediated remyelination was interrogated. ► Olig1 enhances NPC oligodendroglial commitment. ► The absence of Olig1 enhances differentiation of NPCs into astrocytes. ► Olig1 is required for optimal functional recovery following NPC transplantation.
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Related Topics
Life Sciences Neuroscience Neurology
Preview
Olig1 function is required for remyelination potential of transplanted neural progenitor cells in a model of viral-induced demyelination
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