Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6019009 | Experimental Neurology | 2012 | 8 Pages |
Abstract
⺠Delayed valproic acid injection (8 h following surgery) significantly accelerated recovery of rats with spinal cord injury. ⺠VPA treatment, in a concentration dependent manner, allowed neurons to overcome Nogo-A inhibition of neurite outgrowth. ⺠The protective effects of VPA were associated with enhancing histone acetylation and neurotrophic gene expression.
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Authors
Lei Lv, Xiang Han, Yan Sun, Xin Wang, Qiang Dong,