Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6019012 | Experimental Neurology | 2012 | 8 Pages |
Abstract
⺠Two proteins related to dementia were overexpressed and tested for memory deficits. ⺠TDP-43 gene transfer, but not tau resulted in a memory retention deficit. ⺠Hippocampal loss and gliosis occurred in the TDP-43 rats. ⺠The vector gene transfer models may be useful to study relevant mild impairment.
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Neurology
Authors
Robert D. Dayton, David B. Wang, Cooper D. Cain, Lisa M. Schrott, Julio J. Ramirez, Michael A. King, Ronald L. Klein,