Article ID Journal Published Year Pages File Type
6019017 Experimental Neurology 2012 7 Pages PDF
Abstract
► Glibenclamide (GLIB) is an emerging pharmacotherapy in spinal cord injury (SCI). ► In SCI, an impact force delivered laterally causes unilateral primary hemorrhage. ► Medially, the same force causes bilateral hemorrhage and 45% larger lesions. ► GLIB was highly beneficial with both unilateral and bilateral primary hemorrhage. ► The magnitude of benefit from GLIB depended on the extent of primary hemorrhage.
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