Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6019036 | Experimental Neurology | 2012 | 9 Pages |
Abstract
â¶ The interaction of neurons and microglia is essential in maintaining CNS homeostasis. â¶ Aging and stress lead to heightened neuroinflammation and increased microglial reactivity. â¶ Neuronal control of microglial activation is disrupted by aging, stress and inflammation. â¶ Loss of neuronal-microglial communication has deleterious consequences for brain and behavior.
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Authors
Heidi A. Jurgens, Rodney W. Johnson,