Article ID Journal Published Year Pages File Type
6019083 Experimental Neurology 2012 10 Pages PDF
Abstract
► Symptoms evoked by hemicerebellectomy are reflected by GAP-43 levels modifications. ► GAP-43 mediates retrograde death in pre-cerebellar neurons axotomized by the lesion. ► GAP-43 mediates plastic response in not-axotomized pontine and deep cerebellar nuclei. ► Plasticity of spared ponto-cerebellar circuit precedes and drives functional recovery. ► GAP-43 level in each cerebellar nucleus is related to recovery from specific symptoms.
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