Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6019153 | Experimental Neurology | 2012 | 9 Pages |
Abstract
⺠Anti-ganglioside antibodies are found in neuropathies, AMAN, AMSAN, or ASAN. ⺠Anti-GD1a antibody disrupts nodes of Ranvier and induces nerve conduction block. ⺠Anti-GD1b antibodies disrupt nodes in sensory nerves and cause ataxia. ⺠Anti-GM1 antibodies attack primarily motor but occasionally sensory nodes as well. ⺠Nodal disruption may be a common mechanism in AMAN, AMSAN, and ASAN.
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Authors
Keiichiro Susuki, Nobuhiro Yuki, Dorothy P. Schafer, Koichi Hirata, Gang Zhang, Kei Funakoshi, Matthew N. Rasband,