Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6019189 | Experimental Neurology | 2011 | 10 Pages |
Abstract
âºOlfactory glia stimulate long distance axonal regeneration of retinal ganglion cells axons in the presence of reactive astrocytes. âºOlfactory glia transplanted to the injured optic nerve stimulates regeneration of RGC axons through the injury site and towards the optic chiasm. âºOlfactory glia can be genetically engineered to secrete CNTF. âºOlfactory glia were unable to myelinate RGC axons under the same culture conditions oligodendrocyte precursors can. âºRegeneration of RGC in vitro axons is promoted by a cell surface substrate and/or secreted factor not a secreted factor alone.
Related Topics
Life Sciences
Neuroscience
Neurology
Authors
Giles W. Plant, Alan R. Harvey, Simone G. Leaver, Seok Voon Lee,