| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6019229 | Experimental Neurology | 2011 | 8 Pages |
Abstract
⺠Removal of carbohydrate moieties from rhSGSH reduces its plasma clearance. ⺠Neuropathology was not improved with any formulation of enzyme at any dose. ⺠Modified rhSGSH more effectively degrades primary storage in non-CNS tissues.
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Authors
Tina Rozaklis, Helen Beard, Sofia Hassiotis, Antony R. Garcia, Matthew Tonini, Amanda Luck, Jing Pan, Justin C. Lamsa, John J. Hopwood, Kim M. Hemsley,