Article ID Journal Published Year Pages File Type
6019273 Experimental Neurology 2011 7 Pages PDF
Abstract
►Detection of PrPC variants by differential protein solubility in detergent solutions. ►Glycosylated PrPC is more soluble in detergents than in nonglycosylated isoforms. ►Nonglycosylated PrPC remains insoluble with detergents Triton, CHAPS, and OGP. ►Differentiation by solubility experiments can provide information on PrPC composition.
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Life Sciences Neuroscience Neurology
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