| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 602043 | Colloids and Surfaces B: Biointerfaces | 2010 | 5 Pages |
Abstract
Cell patterning on substrates has played a significant role in the study of basic biology, cell-based biosensor and tissue engineering. In this report, a cell pattern was prepared on poly(dimethylsiloxane) (PDMS) substrate by vacuum ultraviolet (VUV) lithography. After immobilizing allyl-polyethylene glycol (APEG) onto PDMS, a chemical heterogeneous patterned surface was fabricated by VUV (Xe2 excimer: 172 nm) lithography with copper mesh as a photomask. The UV exposed domains can promote L929 cell adhesion and growth. However, non-exposed regions resist cell attachment because of the repelling property of PEG. Therefore, cell pattern could be achieved without pre-adsorption of cell adhesive species before cell culture.
Keywords
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Colloid and Surface Chemistry
Authors
Jinbo Gan, Hong Chen, Feng Zhou, He Huang, Jun Zheng, Wei Song, Lin Yuan, Zhongkui Wu,