| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6021654 | Neurobiology of Disease | 2015 | 14 Pages |
Abstract
TSPO expression was dynamically upregulated during epileptogenesis, persisted in the chronic phase and correlated with microglia activation rather than reactive astrocytes. TSPO expression was correlating with spontaneous seizures and its high expression during the latent phase might possibly suggest being an important switching point in disease ontogenesis which could be further investigated by PET imaging.
Keywords
KASEPBSTSPOThree-dimensional3-Ds.c.GFAPROIdentate hilusTLESRSVOIkainic acidVideo-electroencephalographyMRIcornu ammonisstatus epilepticusEpilepsyMagnetic resonanceseizurespontaneous recurrent seizuresMagnetic resonance imagingvEEGcomputed tomographyPositron emission tomographyvolume of interestsubcutaneousdentate gyrustemporal lobe epilepsyPhosphate buffered salineregion of interestMicrogliaPETglial fibrillary acid proteintranslocator proteinoptical density
Related Topics
Life Sciences
Neuroscience
Neurology
Authors
Halima Amhaoul, Julie Hamaide, Daniele Bertoglio, Stephanie Nadine Reichel, Jeroen Verhaeghe, Elly Geerts, Debby Van Dam, Peter Paul De Deyn, Samir Kumar-Singh, Andrew Katsifis, Annemie Van Der Linden, Steven Staelens, Stefanie Dedeurwaerdere,