PARP-1 activation causes neuronal death in the hippocampal CA1 region by increasing the expression of Ca2Â +-permeable AMPA receptors

Article ID	Journal	Published Year	Pages	File Type
6021886	Neurobiology of Disease	2014	10 Pages	PDF

Keywords

NMDA Cytochrome-c GluA1 PARP NBQX cyt-c AP5 NASPM AMPK nNOS TRPM N-methyl-d-aspartate OGD MNNG Jun N-terminal kinase AMPA mTOR Jnk 2-amino-5-phosphonopentanoate 1-Naphthyl acetyl spermine 5′ AMP-activated protein kinase AIF α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid Par neuronal nitric oxide synthase apoptosis-inducing factor Oxygen and glucose deprivation Cell death map mammalian target of rapamycin Hippocampus transient receptor potential Propidium iodide Poly(ADP-ribose)Poly(ADP-ribose) polymerase

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PARP-1 activation causes neuronal death in the hippocampal CA1 region by increasing the expression of Ca2Â +-permeable AMPA receptors

Authors

E. Gerace, A. Masi, F. Resta, R. Felici, E. Landucci, T. Mello, D.E. Pellegrini-Giampietro, G. Mannaioni, F. Moroni,