| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6022070 | Neurobiology of Disease | 2014 | 13 Pages |
Abstract
This study identified several signaling pathways possibly involved in temporal lobe epileptogenesis, not previously indicated by RNA microarray studies. These include miRNAs that regulate the ErbB and Wnt pathways and focal adhesion, which may represent interesting new targets for therapeutic interventions.
Keywords
MEK1SV2AMEF2CPHCTLEsynaptic vesicle protein 2ALimk1ERKTGFβmTORLIM domain kinase 1Myocyte enhancer factor 2CmiRNAsJnkc-Jun N-terminal kinaseMAPKarrayepileptogenesisstatus epilepticusTransforming Growth Factor BetamicroRNAsRINRNA Integrity Numberdentate gyrustemporal lobe epilepsyParahippocampal cortexPathwaysRatMiRNAmammalian target of rapamycinHippocampusmitogen-activated protein kinasemitogen-activated protein kinase kinaseextracellular signal-regulated kinase
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Authors
Jan A. Gorter, Anand Iyer, Ian White, Anna Colzi, Erwin A. van Vliet, Sanjay Sisodiya, Eleonora Aronica,