| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6022334 | Neurobiology of Disease | 2013 | 13 Pages |
Abstract
⺠We identify mitochondria respiratory chain protein defects and oxidative stress in autism brain temporal lobe. ⺠We found altered mitochondrial dynamics in autism temporal lobe. ⺠We report the neuronal accumulation of compromised mitochondria in temporal lobe of autism brain. ⺠We detected no mtDNA mutations in ASD brain. ⺠Mechanisms regulating mitochondrial gene transcription are intact in autism brain temporal lobe.
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Authors
Guomei Tang, Puri Gutierrez Rios, Sheng-Han Kuo, Hasan Orhan Akman, Gorazd Rosoklija, Kurenai Tanji, Andrew Dwork, Eric A. Schon, Salvatore DiMauro, James Goldman, David Sulzer,