| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6022338 | Neurobiology of Disease | 2013 | 10 Pages |
Abstract
⺠EAE mice spinal cord shows aberrant vesicular zinc staining in the white matter. ⺠Clioquinol inhibited the daily clinical score and incidence rate of EAE mice. ⺠Clioquinol suppressed demyelination and reduced infiltration of encephalitogenic immune cells. ⺠Clioquinol inhibited the EAE-associated BBB disruption and MMP-9 activation. ⺠Clioquinol increased the induction of autophagy in EAE mice.
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Authors
Bo Young Choi, Bong Geom Jang, Jin Hee Kim, Jae-Nam Seo, Guang Wu, Min Sohn, Tae Nyoung Chung, Sang Won Suh,