Article ID Journal Published Year Pages File Type
6022340 Neurobiology of Disease 2013 12 Pages PDF
Abstract
► GluR2/GAPDH interaction is enhanced in the hippocampus of rats subjected to global ischemia. ► Disruption of GluR2/GAPDH interaction protects against brain damage from global ischemia in the rat hippocampus. ► Disruption of GluR2/GAPDH interaction blocked the decreased GluR2/GAPDH plasma membrane expression in tMCAo rats. ► Disruption of GluR2/GAPDH interaction protects against brain damage from focal ischemia in the rat. ► Inhibition of GAPDH expression protects brain damage from focal ischemia.
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