| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6022346 | Neurobiology of Disease | 2013 | 13 Pages |
Abstract
⺠D-JNKi potently reduces neonatal ischemic brain injury. ⺠Cerebral ischemia induces JNK phosphorylation at the mitochondria. ⺠Mitochondrial integrity is preserved when mitochondrial JNK is not phosphorylated. ⺠D-JNKi reduces pro-apoptotic molecules and increases anti-apoptotic molecules. ⺠Neuroinflammation is strongly reduced after D-JNKi treatment.
Keywords
Related Topics
Life Sciences
Neuroscience
Neurology
Authors
Cora H. Nijboer, Hilde J.C. Bonestroo, Jitske Zijlstra, Annemieke Kavelaars, Cobi J. Heijnen,