| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6022367 | Neurobiology of Disease | 2013 | 10 Pages |
Abstract
⺠Human fMRI identified an anatomical pattern of caudate dysfunction linked to disease phenotype in HD. ⺠Decreased expression levels of WIF-1 and PPP1R7 proteins correlated with human HD-MRI data. ⺠HD mouse fMRI identified a temporal pattern of striatum abnormality. ⺠fMRI guided Western blot analysis in mice confirmed that deficiency in PPP1R7 is correlated with phenotype.
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Authors
Nicole M. Lewandowski, Yvette Bordelon, Adam M. Brickman, Sergio Angulo, Usman Khan, Jordan Muraskin, Erica Y. Griffith, Paula Wasserman, Liliana Menalled, Jean Paul Vonsattel, Karen Marder, Scott A. Small, Herman Moreno,