Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6022370 | Neurobiology of Disease | 2013 | 11 Pages |
Abstract
⺠Normalization of Dyrk1A levels was achieved in trisomic mice using viral particles. ⺠Dyrk1A normalization attenuates hippocampal phenotype in adult trisomic mice. ⺠Dyrk1A is a potential target in adult trisomic mouse models of Down syndrome.
Related Topics
Life Sciences
Neuroscience
Neurology
Authors
Xavier Altafaj, Eduardo D. MartÃn, Jon Ortiz-Abalia, Aitana Valderrama, Cristina Lao-PeregrÃn, Mara Dierssen, Cristina Fillat,