Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6022371 | Neurobiology of Disease | 2013 | 9 Pages |
Abstract
⺠Chemostimulants induced striatal seizures in immature rat brain slices in vitro. ⺠Striatal seizures synchronized with medium spiny neuron hyperexcitability. ⺠Striatal hyperexcitability is developmentally regulated. ⺠Striatal hyperexcitability requires NMDAR activation. ⺠Seizure-like events can form in the isolated striatum.
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Authors
Wilson Yu, Megan Calos, Julie Pilitsis, Damian Seung-Ho Shin,