| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6022376 | Neurobiology of Disease | 2013 | 9 Pages |
Abstract
⺠4AP in vitro induces two types of ictal events in the entorhinal cortex. ⺠They are preceded by an isolated discharge (ISID) or by frequent discharges (FPID). ⺠Glutamatergic receptor antagonists reduced FPIDs but did not influence ISIDs. ⺠HFOs (80-500 Hz) occur more frequently during ISIDs as compared to FPIDs. ⺠Ictal onset patterns resemble those seen in vivo in low-voltage fast-onset seizures.
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Authors
Massimo Avoli, Gabriella Panuccio, Rochelle Herrington, Margherita D'Antuono, Philip de Guzman, Maxime Lévesque,