| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6022389 | Neurobiology of Disease | 2013 | 12 Pages |
Abstract
⺠Scn1a mutant mice had low sociability modeling Dravet syndrome's social behavior. ⺠The mice showed spatial learning deficit that models learning defect of Dravet. ⺠The mice were hyperactive in novel environments modeling ADHD of Dravet. ⺠Nav1.1 haploinsufficiency intrinsically causes sociobehavioral and learning defects.
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Authors
Susumu Ito, Ikuo Ogiwara, Kazuyuki Yamada, Hiroyuki Miyamoto, Takao K. Hensch, Makiko Osawa, Kazuhiro Yamakawa,