Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6022417 | Neurobiology of Disease | 2013 | 11 Pages |
Abstract
⺠We examined MAG and Necl4 in nerve biopsies of CMT1A patients and in C22 mice. ⺠We identified an increase in MAG and decrease of Necl4 in CMT1A and C22 mice. ⺠Ablating MAG in C22 mice results in separation of axons from their myelin sheath. ⺠Our data show that MAG is important for axon-glia contact in a model for CMT1A.
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Authors
Jochen Kinter, Thomas Lazzati, Daniela Schmid, Thomas Zeis, Beat Erne, Roland Lützelschwab, Andreas J. Steck, Davide Pareyson, Elior Peles, Nicole Schaeren-Wiemers,