Article ID Journal Published Year Pages File Type
6022417 Neurobiology of Disease 2013 11 Pages PDF
Abstract
► We examined MAG and Necl4 in nerve biopsies of CMT1A patients and in C22 mice. ► We identified an increase in MAG and decrease of Necl4 in CMT1A and C22 mice. ► Ablating MAG in C22 mice results in separation of axons from their myelin sheath. ► Our data show that MAG is important for axon-glia contact in a model for CMT1A.
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Life Sciences Neuroscience Neurology
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