Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6022441 | Neurobiology of Disease | 2012 | 10 Pages |
Abstract
⺠Innervation of mouse forelimb muscles was assayed by imaging neuronally-expressed YFP. ⺠Symptomatic SOD1-G85R mice lost motor terminals and large-diameter motor axons. ⺠Activation by action potentials was detected as YFP florescence changes in terminals. ⺠> 90% of surviving SOD1-G85R motor terminals remained responsive to stimulation.
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Authors
Khanh T. Nguyen, Zhongsheng Zhang, Ellen F. Barrett, Gavriel David,