Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6022452 | Neurobiology of Disease | 2012 | 10 Pages |
Abstract
⺠We used genetic fate mapping to analyze neuron addition in kindling model of epilepsy. ⺠A prior seizure history proved to be sufficient to cause a pronounced long-term net effect on neuron addition. ⺠An ongoing occurrence of seizures did not further increase the absolute number of new granule cells. ⺠However, seizure density influenced the relative portion of new cells among all granule cells.
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Authors
Mehrnoosh Jafari, Jonna Soerensen, Renée Marie BogdanoviÄ, Leda Dimou, Magdalena Götz, Heidrun Potschka,