Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6022459 | Neurobiology of Disease | 2012 | 12 Pages |
Abstract
⺠Neocortical stroke in rats opens the BBB in the adjacent hippocampus (12-24 h). ⺠BBB opening in the hippocampus is associated with SDs and epileptiform activity (EA). ⺠Hippocampal exposure to serum and albumin in-vivo/inâvitro is also related to SDs and EA. ⺠The facilitated induction of SDs is related to excessive potassium accumulation. ⺠The induction of SDs and EA seems to depend on NMDA receptor activation.
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Authors
E.G. Lapilover, K. Lippmann, S. Salar, A. Maslarova, J.P. Dreier, U. Heinemann, A. Friedman,