Article ID Journal Published Year Pages File Type
6022496 Neurobiology of Disease 2012 11 Pages PDF
Abstract
► Pyruvate incubation increases the tolerance of neuron to delayed glucose deprivation. ► Improved function during glucose deprivation is mediated by increased glycogen store. ► Tolerance during glucose deprivation is proportional to the amount of glycogen utilized. ► Pyruvate maintains NADH/NAD+ and ATP better during delayed GD than lactate.
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