| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6022501 | Neurobiology of Disease | 2012 | 13 Pages |
Abstract
⺠Mitochondrial preconditioning induced by cyanide protects brain endothelial and neuronal cells against glucotoxicity. ⺠Mitochondrial preconditioning involves a spatial and structural reorganization of the mitochondrial network. ⺠Functional mitochondria are required for brain endothelial and neuronal cells tolerance. ⺠A crosstalk between mitochondrial reactive oxygen species and hypoxia inducible factor 1alpha underlies brain cells tolerance.
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Authors
Sónia C. Correia, Renato X. Santos, Sandra M. Cardoso, Maria S. Santos, Catarina R. Oliveira, Paula I. Moreira,