Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6022502 | Neurobiology of Disease | 2012 | 15 Pages |
Abstract
⺠Pdss2 knockout in the developing cerebellum causes cerebellum hypoplasia. ⺠Pdss2 knockout retards the growth of radial glial cells and impairs cell migration. ⺠Pdss2 knockout may trigger apoptosis via defective mitochondria. ⺠Pdss2 knockout in Purkinje cells after birth may lead to cerebellar ataxia.
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Neurology
Authors
Song Lu, Lin-Yu Lu, Meng-Fei Liu, Qiu-Ju Yuan, Mai-Har Sham, Xin-Yuan Guan, Jian-Dong Huang,