Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6022511 | Neurobiology of Disease | 2012 | 8 Pages |
Abstract
⺠We found increased peptidergic nerve fiber densities in diabetic skin. ⺠Anti-nerve growth factor inhibited the increased peptidergic nerve fiber densities. ⺠SB203580 inhibited the upregulation of peptidergic nerve fiber densities. ⺠Nerve growth factor/p38 signaling mediates increased nerve fibers in diabetic skin.
Keywords
IGTPDNIENFDPGPNGFIFGCGRPSTZPBSDMSOMechanical allodyniaimpaired glucose toleranceImpaired fasting glucosestreptozotocinIntraepidermal nerve fibersTrkType 2 diabetesDimethyl sulfoxidenerve growth factorPhosphate buffered salineSubstance PCSFCerebrospinal fluidpainful diabetic neuropathyprotein gene productcalcitonin gene related peptide
Related Topics
Life Sciences
Neuroscience
Neurology
Authors
Hsinlin T. Cheng, Jacqueline R. Dauch, John M. Hayes, Brandon M. Yanik, Eva L. Feldman,