Article ID Journal Published Year Pages File Type
6022519 Neurobiology of Disease 2012 7 Pages PDF
Abstract
► Thiazolidinedione elevated the cortical transcriptional profiles in HD mice. ► Thiazolidinedione reduced cortical mHtt aggregates in HD mice. ► Rosiglitazone protected neuronal cells from mHtt-evoked mitochondrial deficiency.
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PPARgamma rescue of the mitochondrial dysfunction in Huntington's disease
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